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A novel carboxylesterase drives insecticide cross resistance in the malaria mosquito | News

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09.12.2025

A novel carboxylesterase drives insecticide cross resistance in the malaria mosquito

IMBB researchers collaborating with LSTM, UK, applied a predictive chemoproteomic framework with activity-based protein profiling, identified and functionally validated carboxylesterase Coeae6g as a novel mediator of resistance to insecticides, the cornerstones of the malaria transmitting mosquitoes’ control, with important implications for disease prevention.

[Nature Communications] [Press Release]