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Caloric restriction mimetic enhances remyelination by promoting a less inflammatory environment | News

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17.08.2023

Caloric restriction mimetic enhances remyelination by promoting a less inflammatory environment

IMBB researchers showed that NAM, a form of vitamin B3, can enhance myelin production after demyelination by signaling to microglia to stop causing myelin damage and to astrocytes to reduce inflammation. NAM is an FDA-approved caloric restriction mimetic that induces autophagy