The article is currently available only in Greek.
R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage
IMBB Researchers revealed that DNA damage triggers the release of cytoplasmic ssDNAs leading to chronic inflammation in mice. The team has developed a therapeutic strategy to deliver recombinant nucleases in vivo and remove cytoplasmic ssDNAs, alleviating inflammation.
[Pubmed] [Press Release]
