Konstantinos Theodorakis (Staff Scientist - Karagogeos Lab)

My scientific interests focus on the biology of the nervous system and especially on neuronal development and axoglial interactions during myelination.
I have participated in several research projects related to myelination and demyelinating diseases. Since 2018 we have initiated two research projects concerning the use of biobased and biocompatible nanomolecules for drug encapsulation and drug delivery. Our main goal is the use of novel nanoparticles to deliver known agents that could improve remyelination in vivo. In particular, we are currently working on “NANOMYTHiC” - (T2EDK-00501) , a program where we employ innovative nanocarriers for the targeted and prolonged treatment of demyelinating diseases of the central nervous system.
During my scientific career I have worked with multiple experimental models, such as chick embryos, mice, and various mammalian neuronal and other cell lines.
My technical expertise includes several molecular and biochemical techniques, like gene cloning, PCR, mouse genetics, protein and mRNA expression analysis (immunohistochemistry/immunofluorescence and in situ hybridization respectively), real time PCR, cell culture, tissue cultures, brain slice electroporation, FACS, in utero electroporation etc.