espa logo

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes | News

News
Home > News
08.11.2023

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes

IMBB researchers disclose an essential role for XPF with TOP2B and the CTCF/cohesin complex in R-loop processing for transcription activation with important ramifications for DNA repair-deficient syndromes associated with transcription-associated DNA damage.