Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA. (2024) Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence. Nat Commun. 15:4061.
Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou-Clocher A, Tsamardinos I, Topalis P, Austin C, Bouwman BAM, Crosetto N, Altmüller J, Garinis GA. (2023) XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes. Sci Adv. 9:eadi2095.
Bujarrabal-Dueso A, Sendtner G, Meyer DH, Chatzinikolaou G, Stratigi K, Garinis GA, Schumacher B. (2023) The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities. Nat Struct Mol Biol. 30:475-488.
Tsekrekou M, Stratigi K, Chatzinikolaou G. (2017) The nucleolus: in genome maintenance and repair. Int J Mol Sci. 18:1411.
Chatzinikolaou G, Apostolou Z, Aid-Pavlidis T, Ioannidou A, Karakasilioti I, Papadopoulos GL, Aivaliotis M, Tsekrekou M, Strouboulis J, Kosteas T, Garinis GA. (2017) ERCC1–XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes. Nat Cell Biol. 19:421-432.
Publications in peer‑reviewed international scientific journals
- Braun F., Mandel A.M., Blomberg L., Wong N., Chatzinikolaou G., Meyer D.H., Reinelt A., Nair V., Akbar-Haase R., McCown P.J., Haas F., Chen H., Rahmatollahi M., Fermin D., Ebbestad R., Slaats G.G., Bork T., Schell C., Koehler S., Brinkkoetter P.T., Lindenmeyer M.T., Cohen C., Kann M., Unnersjö-Jess D., Bloch W. ,Sampson M.G., Et Dollé M., Puelles V.J. , Kretzler M., Garinis G.A. , Huber T.B., Schermer B., Benzing T., Schumacher B., Kurschat C.E. Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage. JCI Insight, May 20;10(12):e172370, 2025.
- Siametis A.*, Stratigi K.*, Giamaki D., Chatzinikolaou G., Akalestou Clocher A., Luke b., Schumacher B., Garinis G.A. Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence. Nature Communications, May 14;15(1):4061, 2024.
- Chatzinikolaou G.*, Stratigi K.*, Siametis A., Goulielmaki E., Akalestou-Clocher A., Tsamardinos I., Topalis P., Austin C., Bouwman B.A., Crosetto N., Altmüller J., Garinis G.A. XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes. Science Advances, Nov 10;9(45):eadi2095, 2023.
- Bujarrabal-Dueso A., Sendtner G., Meyer D.H., Chatzinikolaou G., Stratigi K., Garinis G.A., Schumacher B. The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities. Nature Structural and Molecular Biology, Apr;30(4):475-488, 2023.
- Goulielmaki E.*, Tsekrekou M.*, Batsiotos N., Ascensão-Ferreira M., Ledaki E., Stratigi K., Chatzinikolaou G., Topalis P., Kosteas T., Altmüller J., Demmers J.A., Barbosa-Morais N.L., Garinis G.A. The splicing factor XAB2 interacts with ERCC1-XPF and XPG for RNA-loop processing during mammalian development. Nature Communications, May 26;12(1):3153, 2021.
- Goulielmaki E.*, Ioannidou A.*, Tsekrekou M., Stratigi K., Poutakidou I.K., Girtzimanaki K., Aivaliotis M., Evangelou K., Topalis P., Altmller J., Gorgoulis G.V., Chatzinikolaou G., Garinis G.A. Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage. Nature Communications, Jan 2;11(1):42, 2020.
- Apostolou Z., Chatzinikolaou G., Stratigi K., Garinis G.A. Nucleotide excision repair and transcription-associated genome instability. Bioessays, Apr;41(4):e1800201, 2019.
- Tsekrekou M., Stratigi and Chatzinikolaou G. The nucleolus: in genome maintenance and repair. International Journal of Molecular Sciences, Jul 1;18(7), 2017.
- Chatzinikolaou G.*, Apostolou Z.*, Aid-Pavlidis T., Ioannidou A., Karakasilioti I., Papadopoulos G.L., Aivaliotis M., Tsekrekou M., Strouboulis J., Kosteas and Garinis G.A. ERCC1–XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes. Nature Cell Biology, May;19(5):421-432, 2017.
- Chatzinikolaou G., Karakasilioti I., Garinis G.A. DNA damage and innate immunity: links and trade-offs. Trends in Immunology, Sep;35(9):429-35, 2014.
- Karakasilioti I., Kamileri I., Chatzinikolaou G., Kosteas T., Vergadi E., Robinson A.R., Tsamardinos I., Rozgaja T.A., Siakouli S., Tsatsanis C., Niedernhofer L.J., Garinis G.A. DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria. Cell Metabolism, Sep 3;18(3):403-15, 2013.
- Nikitovic D., Chatzinikolaou G., Tsiaoussis J., Tsatsakis A., Karamanos NK.,Tzanakakis GN. Insights into targeting colon cancer cell fate at the level of proteoglycans/glycosaminoglycans. Current Medicinal Chemistry, Jun 18, 2012.
- Chatzinikolaou G., Nikitovic D., Berdiaki A., Zafiropoulos A., Katonis P., Karamanos NK., Tzanakakis GN. Heparin regulates colon cancer cell growth through p38 mitogenactivated protein kinase signalling. Cell Proliferation, 43(1): 9-18, 2010.
- Chatzinikolaou G., Nikitovic D., Asimakopoulou A., Tsatsakis A., Karamanos NK., Tzanakakis GN. Heparin a unique stimulator of human colon cancer cells’ growth. IUBMB Life, 60: 333-340, 2008.
- Zafiropoulos A., Fthenou E., Chatzinikolaou G., Tzanakakis GN. Glycosamino-glycans and PDGF signaling in mesenchymal cells. Connective Tissue Research, 49: 153-156, 2008.
- Chatzinikolaou G., Nikitovic D., Stathopoulos EN., Velegrakis GA., Karamanos NK., Tzanakakis GN. Protein tyrosine kinase and estrogen receptor dependent pathways regulate the synthesis and distribution of glycosaminoglycans/proteoglycans produced by two human colon cancer cell lines. Anticancer Research, 27: 4101-4106, 2007.
