The facility can be used to design and perform several electrophysiological protocols from a variety of preparations
a) short-term and long-term plasticity experiments from brain slices of various cortical areas, the hippocampus or amygdala
b) current-clamp recordings to study neuronal excitability, spontaneous or evoked synaptic responses from brain slices with pharmacological applications if necessary.
c) recordings can also be performed from YFP or GFP- labeled cells, either from brain slices or neuronal cultures
d) voltage-clamp recordings to study spontaneous excitatory and/or inhibitory activity from PC12 and/or primary neuronal cultures cells with pharmacological applications if necessary
e) two-electrode voltage-clamp recordings from Xenopus oocytes
Other specialized protocols could also be performed upon request, given the suitability of existing equipment.

Current projects
1. Adaptations in neuronal excitability and synaptic plasticity following behavioral memory training
2. Defining the critical period in synaptic plasticity processes within the prefrontal cortex
3. Cellular and network activity adaptations in transgenic mice with reduced number of cortical interneurons (in collaboration with Domna Karagogeos)
4. Adaptations in neuronal excitability and synaptic plasticity in mouse models of schizophrenia-like symptoms
5. Effect of neurosteroids on short-term and long-term plasticity processes in the hippocampus (in collaboration with Achilleas Gravanis and Ioannis Charalampopoulos)