Christos (Kitsos) Louis

PUBLICATIONS OF THE GROUP (since 2001)

Louis C. (2016) Médecins Sans Frontières and the refugee crisis in Greece: An interview with Dr. Apostolos Veizis. Pathog Glob Health. 110(6):219-222. (PMID: 27348132)

Mitraka E, Topalis P, Dritsou V, Dialynas E, Louis C. (2015) Describing the breakbone fever: IDODEN, an ontology for dengue fever. PLoS Negl Trop Dis. 9(2):e0003479. (PMID: 25646954)

Dritsou V, Topalis P, Windbichler N, Simoni A, Hall A, Lawson D, Hinsley M, Hughes D, Napolioni V, Crucianelli F, Deligianni E, Gasperi G, Gomulski LM, Savini G, Manni M, Scolari F, Malacrida AR, Arcà B, Ribeiro JM, Lombardo F, Saccone G, Salvemini M, Moretti R, Aprea G, Calvitti M, Picciolini M, Papathanos PA, Spaccapelo R, Favia G, Crisanti A, Louis C. (2015) A draft genome sequence of an invasive mosquito: an Italian Aedes albopictus. Pathog Glob Health. 109(5):207-20. (PMID: 26369436)

Neafsey DE, Waterhouse RM, Abai MR, Aganezov SS, Alekseyev MA, Allen JE, Amon J, Arcà B, Arensburger P, Artemov G, Assour LA, Basseri H, Berlin A, Birren BW, Blandin SA, Brockman AI, Burkot TR, Burt A, Chan CS, Chauve C, Chiu JC, Christensen M, Costantini C, Davidson VL, Deligianni E, Dottorini T, Dritsou V, Gabriel SB, Guelbeogo WM, Hall AB, Han MV, Hlaing T, Hughes DS, Jenkins AM, Jiang X, Jungreis I, Kakani EG, Kamali M, Kemppainen P, Kennedy RC, Kirmitzoglou IK, Koekemoer LL, Laban N, Langridge N, Lawniczak MK, Lirakis M, Lobo NF, Lowy E, MacCallum RM, Mao C, Maslen G, Mbogo C, McCarthy J, Michel K, Mitchell SN, Moore W, Murphy KA, Naumenko AN, Nolan T, Novoa EM, O'Loughlin S, Oringanje C, Oshaghi MA, Pakpour N, Papathanos PA, Peery AN, Povelones M, Prakash A, Price DP, Rajaraman A, Reimer LJ, Rinker DC, Rokas A, Russell TL, Sagnon N, Sharakhova MV, Shea T, Simão FA, Simard F, Slotman MA, Somboon P, Stegniy V, Struchiner CJ, Thomas GW, Tojo M, Topalis P, Tubio JM, Unger MF, Vontas J, Walton C, Wilding CS, Willis JH, Wu YC, Yan G, Zdobnov EM, Zhou X, Catteruccia F, Christophides GK, Collins FH, Cornman RS, Crisanti A, Donnelly MJ, Emrich SJ, Fontaine MC, Gelbart W, Hahn MW, Hansen IA, Howell PI, Kafatos FC, Kellis M, Lawson D, Louis C, Luckhart S, Muskavitch MA, Ribeiro JM, Riehle MA, Sharakhov IV, Tu Z, Zwiebel LJ, Besansky NJ. (2015) Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes. Science. 347(6217) (PMID: 25554792)

Saccone G, Louis C, Zhang H, Petrella V, Di Natale M, Perri M, Salvemini M. (2014) Male-specific phosphorylated SR proteins in adult flies of the Mediterranean fruitfly Ceratitis capitata. BMC Genet.;15 Suppl 2:S6. (PMID: 25472723)

Dritsou V, Deligianni E, Dialynas E, Allen J, Poulakakis N, Louis C, Lawson D, Topalis P. (2014) Non-coding RNA gene families in the genomes of anopheline mosquitoes. BMC Genomics.5:1038 (PMID: 25432596)

Guerreiro A, Deligianni E, Santos JM, Silva PA, Louis C, Pain A, Janse CJ, Franke-Fayard B, Carret CK, Siden-Kiamos I, Mair GR. (2014) Genome-wide RIP-Chip analysis of translational repressor-bound mRNAs in the Plasmodium gametocyte. Genome Biol.15(11):493. (PMID: 25418785)

Andreadaki M, Morgan RN, Deligianni E, Kooij TW, Santos JM, Spanos L, Matuschewski K, Louis C, Mair GR, Siden-Kiamos I. (2014) Genetic crosses and complementation reveal essential functions for the Plasmodium stage-specific actin2 in sporogonic development. Cell Microbiol. 16(5):751-67. (PMID: 24471657)

Mitraka E, Stathopoulos S, Siden-Kiamos I, Christophides GK, Louis C. (2013) Asaia accelerates larval development of Anopheles gambiae.Pathog Glob Health. 107(6):305-11. (PMID: 24091152)

Topalis P, Mitraka E, Dritsou V, Dialynas E, Louis C. (2013) IDOMAL: the malaria ontology revisited.J Biomed Semantics.4(1):16. (PMID: 24034841)Favia, G., Lanfrancotti, A., Spanos, L., Caruso M., Sidén-Kiamos, I., Coluzzi, M. and Louis, C. (2001). Molecular characterization of ribosomal DNA (rDNA) polymorphisms discriminating among chromosomal forms of Anopheles gambiae s.s.. Insect Mol. Biol. 10, 19-23. (PMID: 11240633)

Deligianni E, Morgan RN, Bertuccini L, Wirth CC, Silmon de Monerri NC, Spanos L, Blackman MJ, Louis C, Pradel G, Siden-Kiamos I. (2013). A perforin-like protein mediates disruption of the erythrocyte membrane during egress of Plasmodium berghei male gametocytes. Cell Microbiol. 15(8):1438-55. (PMID: 23461714)

Parikh PP, Zheng J, Logan-Klumpler F, Stoeckert CJ Jr, Louis C, Topalis P, Protasio AV, Sheth AP, Carrington M, Berriman M, Sahoo SS. (2012). The Ontology for Parasite Lifecycle (OPL): towards a consistent vocabulary of lifecycle stages in parasitic organisms.J Biomed Semantics. 3(1):5. (PMID: 22621763)

Louis C. (2012). Daily newspaper view of dengue fever epidemic, Athens, Greece, 1927-1931. Emerg. Infect Dis. 18(1):78-82. (PMID: 22257469)Vlachou*, D., Lycett*, G., Sidén-Kiamos, I., Blass, C., Sinden, R.E. and Louis, C. (2001) Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes. Molec. Biochem. Parasit. 112, 229-237. (PMID: 11223130)

Megy K, Emrich SJ, Lawson D, Campbell D, Dialynas E, Hughes DS, Koscielny G, Louis C, Maccallum RM, Redmond SN, Sheehan A, Topalis P, Wilson D; VectorBase Consortium. (2012) VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics. Nucleic Acids Res. 40(Database issue):D729-34. (PMID: 22135296)

Siden-Kiamos I, Louis C, Matuschewski K. (2012) Evidence for filamentous actin in ookinetes of a malarial parasite.Mol Biochem Parasitol. 181(2):186-9. (PMID: 22101204)

Siden-Kiamos I, Schüler H, Liakopoulos D, Louis C. (2010) Arp1, an actin-related protein, in Plasmodium berghei. Mol Biochem Parasitol. 173(2):88-96. (PMID: 20580650)

Sidén-Kiamos I, Louis C. (2008) Intracellular calcium levels in the Plasmodium berghei ookinete.Parasitology. 135(12):1355-62. (PMID:18775093)

Vontas J, Blass C, Koutsos AC, David JP, Kafatos FC, Louis C, Hemingway J, Christophides GK, Ranson H. (2005) Gene expression in insecticide resistant and susceptible Anopheles gambiae strains constitutively or after insecticide exposure. Insect Mol Biol. 14(5):509-21. (PMID: 16164607)

Benos, P.V., Gatt, M.K., Murphy, L., Harris, D., Barrell, B., Ferraz, C., Vidal, S., Brun, C., Demaille, J., Cadieu, E., Dreano, S., Gloux, S., Lelaure, V., Mottier, S., Galibert, F., Borkova, D., Minana, B., Kafatos, F.C., Sidén-Kiamos, I., Bolshakov, S., Papagiannakis, G., Spanos, L., Louis, C., Madueno, E., de Pablos, B., Modolell, J., Peter, A., Schöttler, P., Werner, M., Mourkioti, F., Beinert, N., Dowe, G., Schäfer, U., Jäckle, H., Bucheton, A., Callister, D., Campbell, L., Henderson, N.S., McMillan, P.J., Salles, C., Tait, E., Valenti, P., Pachter, L., Saunders, R.D.C., Glover, D.M. and Ashburner, M. (2001) From First Base: The sequence of the tip of the X chromosome of D. melanogaster. Genome Res., 11, 710-730. (PMID: 11337470)

Mahairaki, V., Lycett, G., Blass, C., and Louis, C. (2001). Beta-integrin of Anopheles gambiae: mRNA cloning and analysis of structure and expression. Insect Mol. Biol. 10: 217-223. (PMID: 11437913)

Louis, C. (2001) Review: a comprehensive set of sequence analysis programs for the VAX. The Biochemist, 23, 64. (PMID: n.a.)

Lycett, G., Blass, C., and Louis, C. (2001) Developmental variation in epidermal growth factor receptor size and localisation in the malaria mosquito, Anopheles gambiae. Insect Mol. Biol., 10, 619-628. (PMID: 11903632)

Bolshakov, V. N. and Louis, C. (2002) Sequencing of complex eukaryotic genomes: man, worm and fruitfly. In: Genome sequencing and comparative analysis (Tsaftaris, A.S., and Polidoros, A.N., eds.) University Studio Press, Thessaloniki. p. 119-131. (PMID: n.a.)

Bolshakov, V., Topalis, P., Blass, C., della Torre, A., Kafatos, F.C. and Louis, C. (2002) A comparison of the genomes of the fruitfly Drosophila melanogaster and the malaria mosquito Anopheles gambiae based on long-range genomic sequences and EST analysis. Genome Res. 12, 57-66. (PMID: 11337470)

Arcà, B., Lombardo, F., Lanfrancotti, A., Spanos, L., Veneri, M., Louis, C. and Coluzzi, M. (2002) A cluster of four D7-related genes are expressed in the salivary glands of the African malaria vector Anopheles gambiae. Insect Mol. Biol.., 11, 47-56. (PMID: 11841502)

Peter, A., Schottler, P., Werner, M., Beinert, N., Dowe, G., Burkert, P., Mourkioti, F., Dentzer, L., He, Y., Deak, P., Benos, P.V., Gatt, M.K., Murphy, L., Harris, D., Barrell, B., Ferraz, C., Vidal, S., Brun, C., Demaille, J., Cadieu, E., Dreano, S., Gloux, S., Lelaure, V., Mottier, S., Galibert, F., Borkova, D, Minana, B., Kafatos, F.C., Bolshakov, S., Siden-Kiamos, I., Papagiannakis, G., Spanos, L., Louis. C, Madueno, E., de Pablos, B., Modolell, J., Bucheton, A., Callister, D., Campbell, L., Henderson, N.S., McMillan, P.J., Salles, C., Tait E., Valenti, P., Saunders, R.D., Billaud, A., Pachter, L., Klapper, R., Janning, W., Glover, D.M., Ashburner, M., Bellen, H.J., Jackle, H., and Schafer, U. (2002) Identification and mapping of vital gene functions of the Drosophila X-chromosome. EMBO Rep. 3, 34-38. (PMID: 11751581)

Holt, R.A., Subramanian, G.M., Halpern, A., Sutton, G.G., Charlab, R., Ribeiro, D.M.C., Wides, R., Salzberg, S.L., Loftus, B., Yandell, M., Majoros, W.H., D.B., Rusch, Lai, Z., Kraft, C.L., Abril, J.F., Anthouard, V., Arensburger, P., Atkinson, P.W., Baden, H., de Berardinis, V., Baldwin, D., Benes, V., Biedler, J., Blass, C., Bolanos, R., Boscus, D., Barnstead, M., Cai, S., Center, A., Chatuverdi, K., Christophides, G.K., Chrystal, M.A., Clamp, M., Cravchik, A., Curwen, V., Dana, A., Delcher, A., Dew, I., Evans, C.A., Flanigan, M., Grundschober-Freimoser, A., Friedli, L., Gu, Z., Guan, P., Guigo, R., Hillenmeyer, M.E., Hladun, S.L., Hogan, J.R., Hong, Y.S., Hoover, J., Jaillon, O., Ke, Z.,1, Kodira, C., Kokoza, E., Koutsos, A., Letunic, I., Levitsky, A., LiangY., Lin, J.J., Lobo, N.F., Lopez, J.R., MalekJ.A., McIntosh, T.C., Meister, S., Miller, J., Mobarry, C., Mongin, E., Murphy, S.D., O’Brochta, D.A., Pfannkoch, C., Qi, R., Regier, M.A., Remington, K., Shao, H., Sharakhova, M., Sitter, C.D., Shetty, J., Smith, T.J., Strong, R., Sun, J., Thomasova, D., Ton, L.Q., Topalis, P., Tu, Z., Unger, M.F., Walenz, B., Wang, A., Wang,J., Wang,M., Wang, X., Woodford, K.J., Wortman,J.R., Wu, M., Yao, A., Zdobnov, E.M., Zhang, H., Zhao, Q., Zhao, S., Zhu, S.C., Zhimulev, I., Coluzzi,M., della Torre,A., Roth, C.W., Louis, C., Kalush, F., Mural, R.J., Myers, E.W., Adams, M.D., Smith, H.O., Broder, S., Gardner, M.J., Fraser, C.M., Birney, E., Bork, P., BreyP.T., Venter, J.C., Weissenbach, J., Kafatos,F.C., Collins, F.H., Stephen L. Hoffman, S.L. (2002) The Genome Sequence of the Malaria Mosquito Anopheles gambiae; Science 298, 129-149. (PMID: 12364791)

Zdobnov, E.M., v. Mering, C., Letunic, I., Torrents, D., Suyama, M., Copley, R.R., Christofides, G.K., Thomasova, D., Holt, R.A., Subramanian, G.M., Mueller, H.M., Dimopoulos, G., Law, J.H., Wells, M.A., Birney, E., Charlab, R., Halpern, A.L., kokoza, E., Kraft, C.L., Zhogwu, L., Lewis, S., Louis, C., Barillas-Mury, C., Nusskern, D., Rubin, G.M., Salzberg, S.L., Sutton, G.G., Topalis, P., Wides, R., Wincker, P., Yandell, M., Collins, F.H., Ribeiro, J., Gelbart, W.M., Kafatos, F.C. and Bork, P. (2002) Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Science, 298, 149-159. (PMID: 12364792)

Topalis, P., Koutsos, A. and Louis, C. (2002) An Anopheles Database (AnoBase). Accessible (from October 2002) through WWW at the URL: http://www.anobase.org. (PMID: n.a.)

Parmakelis, A., Spanos, L., Papagiannakis, G., Louis, C. and Mylonas, M. (2003) Mitochondrial DNA phylogeny and morphological diversity in the genus Mastus (Beck, 1837). A study in a recent (Holocene) island group (Koufonissi, SE Crete). Biol. J. Linnean Soc., 78, 383-399. (PMID: n.a., doi:10.1046/j.1095-8312.2003.00152.x )

Louis, C. (2003) Genomics and Medical Entomology: a Sweet and Fruitful Marriage Blessed with Many Children. Rev. Clin. Pharmacol. Pharmacokin. 18, 234-238. (PMID: n.a.).

Dessens, T.J., Sidén-Kiamos, I., Mendoza, J., Macheraki, V., Khater, E., Vlachou, D., Xu, X.J., Kafatos, F.C., Louis, C., Dimopoulos, G. and Sinden, R.E. (2003). SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development. Mol. Microbiol., 449, 319-329. (PMID: 12828632)

Louis, C. (2003). Medical entomology and genomics [in Greek]. BIO, 7, 34-38. (PMID: n.a.)

Louis, C. (2003). Biology and the Orthodox Academy of Crete. [in Greek] Dialogoi Katallagis, 71, 714-716. (PMID: n.a.)

Louis, C. (2003). Gene Bank Data for Hematophagous Arthropods. In: The Biology of Disease Vectors, Second Edition (Marquardt, W.C., Black, W.C., Freier, J., Hagedorn, H., Hemingway, J., Higgs, S., James, A.A. and Kondratieff, B., eds.) Academic Press. pp.693-697, ISBN: 0-12-473276-3 (PMID: n.a.)

Milgram, A. J., Birney, E., Jasny, B. R., Collins, F., Louis, C., and Roos, D. R. (2003). The Mosquito Genome. CD published by the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) and the American Association for the Advancement of Science (Science). (PMID: n.a.)

James, A.A. and Louis, C., Rapporteurs (2003) Insect Vectors and Human Health. Report of the Scientific Working Group meeting, 12-16 August 2002, Geneva, Switzerland. WHO/TDR Publications, pp.1-73. (PMID: n.a., download from TDR)

Mongin, M., Louis, C., Holt, R. A., Birney, E. and Collins, F. H. (2004). The Anopheles gambiae genome: an update on sequence, data, annotation and access. Trends Parasitol., 20, 49-52. (PMID: 14747013)

Louis, C. (2004). Preface. Insect Biochem. Molec. Biol., 34, 597. (PMID: n.a., doi:10.1016/j.ibmb.2004.03.011)

Siden-Kiamos, I. and Louis, C. (2004). Interactions between malaria parasites and their mosquito hosts in the midgut Insect Biochem. Molec. Biol., 34, 679-685. (PMID: 15242709).

Vontas, J., McCarroll, L., Karunaratne, S.H.P.P., Louis, C., Hurd, H. and Hemingway, J. (2004) Does environmental stress affect insect-vectored parasite transmission? Physiol. Entomol. 29, 210-213. (PMID: n.a., doi:10.1111/j.0307-6962.2004.00410.x).

Ribeiro, J.M.C., Topalis, P. and Louis, C. (2004) AnoXcel: A database of Anopheles gambiae proteins oriented to the bench scientist. Insect Mol. Biol. 13, 449-457 (PMID: 15373803).

Vontas, J., Sidén-Kiamos, I., Papagiannakis, G., Karras, M., Waters, A.P. and Louis, C. (2005) Gene expression in Plasmodium berghei during invasion in an Aedes- parasite co-culture in vitro. Molec. Biochem. Parasit. 139, 1-13 (PMID: 15610814).

Mahairaki, V., Voyatzi, T., Siden-Kiamos, I. and Louis, C. (2005). The Anopheles gambiae gamma1 laminin directly binds the Plasmodium berghei circumsporozoite- and TRAP-related protein (CTRP). Molec. Biochem. Parasit. 140, 119-121. (PMID: 15694493).

David, J.P., Strode, C., Vontas, J., Nikou, D., Vaughan, A., Pignatelli, P.M., Louis, C., Hemingway, J. and Ranson, H. (2005) The Anopheles gambiae Detoxification Chip: a new highly specific microarray to study metabolic based insecticide resistance in malaria vectors. Proc. Natl. Acad. Sci. USA 102, 4080-4084. (PMID: 15753317)

Lombardo, F., Nolan, T., Lycett, G., Lanfrancotti, A., Stich, N., Catteruccia, F., Louis, C., Coluzzi, M. and Arca, B. (2005) An Anopheles gambiae salivary gland promoter analysis in Drosophila melanogaster and Anopheles stephensi. Insect Mol. Biol. 14, 207-216. (PMID: 15796754).

Kotsyfakis, M., Ehret-Sabatier, L., Siden-Kiamos, I., Mendoza, J., Sinden, R.E. and Louis, C. (2005) Plasmodium berghei ookinetes bind to Anopheles gambiae and Drosophila melanogaster annexins. Molec. Microbiol.; 57, 171-179. (PMID: 15948958).

Parmakelis, A., Pfenninger, M., Spanos, L., Papagiannakis, G., Louis, C., and Mylonas, M. (2005) Inference of a radiation in Mastus (Gastropoda, Pulmonata, Enidae) on the island of Crete. Evolution 59, 991-1005. (PMID: 16136799).

Arrighi, R.B.G., Lycett, G., Mahairaki, V., Sidén-Kiamos, I. and Louis, C. (2005) Laminin and the malaria parasite’s journey through the mosquito midgut. J. Exp. Biol., 208, 2497-2502. (PMID: 15961736).

Louis, C. (2005) O Mosquito transgenico [in Portuguese]. Ciencia Hoje 36, 6-8.(PMID: n.a.).

Knols, B.G.J. and Louis, C., eds. (2005) Bridging laboratory and field research for genetic control of disease vectors. (pp. i-x and 1-225). Wageningen UR Frontis Series, Vol. 11, Springer, Heidelberg, Germany, ISBN: 1-4020-3799-6. (PMID: n.a.).

Louis, C. and Knols, B.G.J. (2005) Report of the Working group meeting. In Bridging laboratory and field research for genetic control of disease vectors. (Knols, B. and Louis, C., eds.) Wageningen UR Frontis Series, Vol. 11, Springer, Heidelberg, Germany, ISBN: 1-4020-3799-6. (PMID: n.a.).

Louis, C. (2005) Genomics and expected benefits for vector entomology. In Bridging laboratory and field research for genetic control of disease vectors. (Knols, B. and Louis, C., eds.) Wageningen UR Frontis Series, Vol. 11, Springer, Heidelberg, Germany, ISBN: 1-4020-3799-6. (PMID: n.a.).

Louis, C. (2005) Transition from the laboratory to field and effective interplay. In Bridging laboratory and field research for genetic control of disease vectors. (Knols, B. and Louis, C., eds.) Wageningen UR Frontis Series, Vol. 11, Springer, Heidelberg, Germany, ISBN: 1-4020-3799-6. (PMID: n.a.).

Mahairaki, V., Lycett, G., Sidén-Kiamos, I., Sinden, R.E. and Louis, C. (2005). Close association of invading Plasmodium berghei and beta integrin in the Anopheles gambiae midgut. Arch. Insect Biochem. Physiol. 20, 13-19. (PMID: 16116619)

Vontas, J., Blass, C., Koutsos, A.C., David, J.P., Kafatos, F.C., Louis, C., Hemingway, J., Christophides, G.K., Ranson, H. (2005) Gene expression in insecticide resistant and susceptible Anopheles gambiae strains constitutively or after insecticide exposure. Insect Mol. Biol. 14, 509-521. (PMID: 16164607)

Kotsyfakis, M., Vontas, J., Siden-Kiamos and Louis, C. (2005) The annexin gene family in the malaria mosquito Anopheles gambiae. Insect Mol. Biol. 14, 555-562. (PMID: 16164611)

Topalis, P., Koutsos, A.C., Dialynas, M., Kiamos, C., Hemingway, J. and Louis, C. (2005) AnoBase: A genetic and biological database of anophelines Insect Mol. Biol. 14, 591-597. (PMID: XXX)