Contact
Alex Dömling
Prof, Palackӯ University, CATRIN, Department of Innovative Chemistry
The Dömling lab works for >30 years in the advancement of multicomponent reaction chemistry (MCR): novel synthesis methodologies, stereoselectivity, new chemical space, novel reactions, sustainability, and application of MCR in medicinal chemistry. As an answer to the ever-increasing humanitarian demands of society, the focus of the lab is on novel immuno oncology drugs and antibiotics, facing the rapid and global increase of multiple drug-resistant bacteria causing already now millions of deaths every year. Technologies and methods developed or used in the lab are automation and miniaturization of synthetic chemistry, structure-based drug design, fragment-based drug design, and the use of artificial intelligence methods to accelerate drug discovery.